Best Natural Pde5 Inhibitors List of Foods, Supplements & OTC's

Pde is the abbreviation of phosphodiesterase enzyme. The pde5 inhibitors are the phosphodiesterase type 5 inhibitors. These are the agents which act on the phosphodiesterase enzyme and block the degradative action of cGMP specific pde5 enzyme. Phosphodiesterase type 5 enzyme is present in the cyclic GMP of smooth muscle lining. This smooth muscle lining covers the blood vessels supplying blood to the corpus cavernosum of penis. The pde5 inhibitors are the drugs which are used to treat erectile dysfunction. These drugs are considered the most effective oral treatment of erectile dysfunction.

As phosphodiesterase type 5 enzyme is also present in the smooth muscle lining of arteries, so these drugs are also used to treat pulmonary hypertension. Whenever there is sexual stimulation, the nitric oxide is produced in the corpus cavernosum. Nitric oxide activates another enzyme named guanylate cyclase. This enzyme in turn increases the level of cyclic GMP. Cyclic GMP relaxes the smooth muscles of blood vessels, increased blood flow and erection of penis. Pde5 inhibitors inhibit the degradation of cyclic GMP by the enzyme pde5 itself. And as a result the blood circulation increases and leads to the treatment of erectile dysfunction.

Best Natural Pde5 Inhibitors List of Foods, Supplements & OTC's

Best natural pde5 inhibitors list of supplements


There are many natural supplements which are used as pde5 inhibitors to treat erectile dysfunction. The five main supplements include arginine, pycnogenol, icariin extract, forskolin and tongkat Ali. These supplements are used instead of pde5 inhibitors. Icariin extract is the main ingredient of the horny goat weed. It has effects like testosterone and helps in stimulation of sexual effects. Pycnogenol is extracted from bark of French maritime pine. Forskolin is a fat burner and affects glucoma. It naturally inhibits pde5 enzyme of smooth muscles.  Arginine is also a natural strengthening agent.

Best natural pde5 inhibitors list of foods


There are no foods which can treat erectile dysfunction but some foods are known to help in treatment of erectile dysfunction. These foods are as follows:


  • Leafy greens and beets contains nitrates in them and these nitrates are responsible for nitric oxide production. 
  • Flavanoids present in dark chocolate also helps in the secual stimulation of penis. 
  • Pistachio helps a lot in strengthening of penis because pistachios contain proteins. 
  • Fishes are good for penis working. As fishes contain zinc in them which helps in working of penis. 
  • Watermelon is also useful. 
  • Pomegranate juice is used a lot to combat erectile dysfunction. 


Best natural pde5 inhibitors list of foods OTCs


OTC drugs available for treatment of erectile dysfunction include viagra. But in case viagra is not available, there are many alternatives which may be used for instead of viagra. These alternatives include verdenafil (levitra and staxyn are the brand names), tadalafil (adcirca and Cialis are the brand names of tadalafil) and avanafil (stendra is the brand name). Other than these oral drugs use for erectile dysfunction, other dosage forms include penile injections of alprostadil, phentolamine and papaverine. Urethral suppositories are also available. Testosterone replacement is another treatment Option.
Best Natural Pde5 Inhibitors List of Foods, Supplements & OTC's Best Natural Pde5 Inhibitors List of Foods, Supplements & OTC's Reviewed by Simon Albert on January 03, 2019 Rating: 5
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