Cortical dysplasia Types, Prognosis, Life Expectany, Focal Cortical dysplasia

Cortical dysplasia is an abnormal development of brain in fetus. During the development of brain in fetus, the innermost neurons start spreading outward towards cerebral cortex. Problem in spreading of these neurons to their determined position may cause abnormal bombardment of neurons leading to seizures and epilepsy. It is considered congenital disease. Cortical dysplasia is the most common cause reported behind epilepsy and seizures and it is difficult to treat it with medications inside mother’s womb but in adults anti-convulsants are used to treat this condition. Cortical dysplasia occurs in fetus when the upper most layer is not properly formed.

Cortical dysplasia Types

Cortical dysplasia is categorized into 3 main types and these three types are as follows:

  • Type 1: it is asymptomatic at early stages and mostly occurs in adults after some specific changes in the temporal lobe. During a brain scan, it is very difficult to seen in reports.
  • Type 2: it is most commonly seen in children. The appearance of symptoms are more severe in this type of cortical dysplasia. In this type, both the temporal and frontal lobe are involved.
  • Type 3: this type along with cortical dysplasia involves other parts of brain too because of an early injury of head.

Cortical dysplasia Prognosis

According to the treatment options, the following results can be seen. During a recent study regarding cortical dysplasia, after proper follow ups, 72 % of patients recovered from seizures and epilepsy, 4 % of patients reported with 2 seizures a year and 17 % reported less frequent seizures appearance and remaining 8 % show no improvement. There are many factors effecting the occurrence of seizures like age, surgery and demographic data like sex, onset of seizure at which age, febrile seizures and aura. The types of seizures have no link with the treatment outcome.

Cortical dysplasia Life Expectancy

The expectation of life in patients with cortical dysplasia vary from patient to patient. If the cortical dysplasia got severe in children then the expectation of life is very less as it is very difficult to treat cortical dysplasia in the mother’s womb. In children, the cortical dysplasia is considered fatal because the brain in children is not fully developed and it is quiet complicated to treat seizures. In adults the degree of life expectation increases as they have fully developed brain and most of the cases show better survival after surgery and medications use.

Focal Cortical dysplasia

Focal cortical dysplasia is considered the most common cause behind cortical dysplasia. Focal cortical dysplasia is categorized further into the subtypes 1a, 1b, 2a, 2b, 3a, 3b, and 3c. Focal cortical dysplasia disturbs the normal functioning of brain. Main causes reported for focal cortical dysplasia are intrauterine infection, ischemia and chromosomal mutation like genetic disorder. There are some viruses involved in the spreading of this disease like cytomegalovirus and human papilloma virus. Treatment of focal cortical dysplasia involves the surgical removal of the effected region and also the use of medications like anti convulsants.
Cortical dysplasia Types, Prognosis, Life Expectany, Focal Cortical dysplasia Cortical dysplasia Types, Prognosis, Life Expectany, Focal Cortical dysplasia Reviewed by Simon Albert on April 27, 2017 Rating: 5
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