Myriad Prequel Prenatal Screen: Results, Cost, CPT Code, Gender Accuracy, and Reviews
- What is Myriad Prequel Prenatal Screen?
- Results
- Cost
- CPT Code
- Gender Accuracy
- Reviews
What is Myriad Prequel Prenatal Screen?
The Myriad Prequel Prenatal Screen is a non-invasive prenatal test (NIPT) that analyzes cell-free fetal DNA from maternal blood to detect chromosomal abnormalities such as trisomy 21 (Down syndrome), trisomy 18, and trisomy 13. It can also identify fetal sex and certain microdeletions with high accuracy, offering early genetic insight as early as 10 weeks of pregnancy.

Results
Results are typically available within 5–7 days after the sample reaches the lab. The report indicates low- or high-risk findings for major chromosomal conditions and includes fetal sex results if requested. In rare cases, results may be inconclusive due to low fetal DNA fraction, requiring a repeat sample.
Cost
The test costs around $1,000–$2,000 without insurance, but many patients pay $0–$300 depending on coverage. Myriad offers financial assistance and payment plans for uninsured patients.
CPT Code
Common CPT codes include 81420 (chromosomal aneuploidy NIPT) and 81422 for expanded panels including microdeletions. These codes are used for billing and insurance claims.
Gender Accuracy
The test provides fetal sex determination with over 99% accuracy by detecting Y-chromosome material in maternal blood. This makes it more reliable than early ultrasound scans.
Reviews
Patients and clinicians praise the Prequel test for its speed, accuracy, and non-invasive nature. Reviews highlight its clear reporting and reliability for early pregnancy screening, though some note the cost as a drawback without insurance.
Reviewed by Simon Albert
on
July 08, 2025
Rating: